JAK2 (v617f)

Cat no. YSL-SNP-JAK2-100

JAK2 (v617f)

Cat no. YSL-SNP-JAK2-100

A qPCR genotyping kit for JAK2 (v617f)

JAK2 (V617F) is a genetic mutation commonly associated with myeloproliferative neoplasms, such as polycythemia vera. This mutation results in the overactivation of the JAK-STAT signaling pathway, leading to abnormal blood cell production. Early detection of JAK2 (V617F) is crucial in monitoring disease progression and determining appropriate treatment strategies in the human healthcare sector.

YouSeq's qPCR kit to detect JAK2 (V617F) allows for sensitive and specific identification of this mutation, enabling timely intervention and management of myeloproliferative neoplasms. Rapid detection of JAK2 (V617F) can prevent disease complications and improve patient outcomes in the clinical setting, highlighting the importance of molecular diagnostic tools in precision medicine.

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For Research Use Only. Not intended for diagnostic use.

Contents


Target Specific primer/probe
qPCR MasterMix
2 x Positive control template
DNase/RNase free water
Template resuspension buffer
ROX Passive Reference

Technical specification


Sensitivity: 100 copy detection
Run Time: Approx 1hr30 (dependent on instrumentation)
Detection Channels: FAM & VIC/HEX labelled

Product variants


YSL-SNP-JAK2-100 : Lyophilised version for ambient shipping
YS-SNP-JAK2-100 : Frozen version for dry ice shipping

Pseudonyms

JAK2 (V617F); JAK2 mutation; Janus kinase 2 mutation; myeloproliferative neoplasm; MPN; polycythemia vera; PV; essential thrombocythemia; ET; primary myelofibrosis; PMF; myelofibrosis

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